Erythema gyratum repens is a paraneoplastic rash that often precedes the diagnosis of malignancy by several months. Superficial inflammatory dermatoses are very common and comprise a wide, complex variety of clinical conditions. A differential diagnosis of erythema annulare centrifugum eac, hansens disease, granuloma annulare, atypical mycosis fungoides, and vasculitic annulare erythema were considered. Erythema annulare centrifugum pathology dermnet nz. Histological features of erythema gyratum repens are not diagnostic and include hyperkeratosis, parakeratosis, acanthosis and. Erythema annulare centrifugum eac is a cutaneous reaction pattern with multiple possible underlying. Md from the division of dermatology, department of medicine, and the center for the study of aging, duke university medical center, durham, north carolina. Erythema annulare centrifugum eac is a type of gyrate erythema.
Dermatopathology reference describes erythema dyschromicum perstans ashy dermatosis histopathology including histologic features and. Note that this may not provide an exact translation in all languages. A histopathological study g rolland finlayson, md w mitchell sams, jr. The gyrate erythemas consist of a nonspecific group often called erythema annulare centrifugum for which the cause is usually unknown, and three specific types erythema marginatum rheumaticum, erythema chronicum migrans lyme disease, and erythema gyratum repens. Gyrate erythema superficial or deep figurate erythema. Erythema gyratum repens is a clinically distinctive figurate or annular erythema that is usually associated with underlying malignancy. Erythema annulare centrifugum is a chronic reactive form of annular erythema characterised by erythematous, circular, arciform, and polycyclic lesions, with a characteristic delicate scale behind the advancing edge trailing scale. Authoritative facts about the skin from the dermnet new zealand.
Erythema annulare centrifugum eac is classified as one of the. Histopathological features of the skin lesions showing dense very tight. Pdf erythema annulare centrifugum eac is one of the figurate. To answer those questions, we analyzed 82 biopsy specimens from 73 patients with a clinical and histopathologic diagnosis of erythema annulare centrifugum, gyrate erythema, or figurate erythema. Management of a treatable underlying cause often results in resolution of a gyrate erythema. Accurate histological diagnosis, although it can sometimes be difficult to establish, is essential for clinical management. The eruption is rapidly migrating and composed of concentric rings forming a woodgrain pattern histology of erythema gyratum repens. Histopathological features of the skin lesions showing mild. If eac is due to an underlying disorder, the skin lesions will usually. Pdf erythema annulare centrifugum eac is one of the figurate or annular. Reports suggest that manual rupture of the fibrous bands ensures immediate. Erythema migrans and lyme disease is discussed elsewhere in the cds. Various erytematous eruptions with a curvilinear gyrate appearance. Erythema gyratum repens is not considered a dermatologic emergency in the sense that immediate therapy is required, but it remains a cant miss dermatologic diagnosis.
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