To investigate the hydrating strength and modulatory effect of buchholzia coriacea seed extracts on erythrocyte membrane proteins degradation. At doses of 10 mgkg, 25 mgkg and 50 mgkg, the extracts were tested against eudrilus eugeniae earthworm and bunostomum. Pdf analgesic activity of the methanolic seed extract of. Buchholzia coriacea capparidaceae various parts leaves, seeds, bark of buchholzia coriacea known as wander kola called okpokolo in igbo are used in the traditional treatment of various diseases such as rheumatism, kidney pain, headache, sinusitis, and nasal congestion, smallpox, skin itching, microbial infections, and in the. Chemoprotective effects of butanol fraction of buchholzia. A method for the cosmetic treatment of the skin or scalp and a method for the treatment of skin inflammation includes administering to a patient in need thereof a composition including an effective amount of a plant extract from a plant belonging to the genus buchholzia. This work reports the synthesis of silver nanoparticles agnps using almond leaf extract and the evaluation of its antibacterial activity. Its leaves and stem bark in various formulations, decoctions and concoction exhibit antihelmintic, antimicrobial and cytotoxic effects on microorganism ajaiyeoba et al 2003. Antidepressantlike potentials of buchholzia coriacea seed. Neuroprotective effects of buchholzia coriacea seed. Pdf the antiplasmodial activity of aqueous extract of buchholzia coriacea was investigated in intraperitoneally, malariainduced albino mice using. Antimicrobial, antiinflammatory, and chemical evaluation of.
Different studies have unveiled the traditional usefulness and clinical potentials of buchholzia coriacea, a medicinal plant known for its effectiveness in lowering blood glucose. It is also described as an evergreen understorey tree of forests lowland rainforest. Development of extraction protocol for phenolic compounds in musk tree seed buchholzia coriacea onwuka g. The animals were allowed free access to rat pellets.
Analgesic and antiinflammatory effects of ethanol extracts of. Monitoring of parasitaemia was by the rapid matching technique. The free radical scavenging activity for 2,2diphenyl1picrylhydrazyl. This study investigated the phytochemical content, proximate analysis, acute toxicity test, antimicrobial, and antiinflammatory effect of buchholzia coriacea wonderful kola seed fractions using standard methods. Anthelmintic activities of chloroform and methanol. Investigation of the antitrypanosomal activity of buchholzia coriacea seed extract against a field strain of trypanosoma congolense 1nweze, n. The buchholzia coriacea incorporated rations and standard ration were fed to alloxaninduced diabetic rats for 70 consecutive days. The abundance of plants in the world as vegetables, spices, fruits, etc. Horsfieldia coriacea is a species of plant in the family myristicaceae. Plant material and extraction procedure the buchholzia coriacea seeds were purchased locally from oje market, ibadan, nigeria, and identified at the botany department, university of ibadan, ibadan, nigeria.
It belongs to the family capparidaceae and genus buchholzia. Its phytochemical screening revealed that the seeds contain alkaloids, stem barks contain lupeol, flavonoid, terpenes and steroids. Access is allocated within two business days of purchase and lasts one year. Abstract this study examined the nephrotic effect of buchholzia coriacea formulated diet in sucrosefed pregnant rats and their offspring. Us8603545b2 cosmetic and pharmaceutical uses of an extract. Buchholzia coriacea leaves have been shown to have anthelmintic effects on fasciola hepatica ajaiyeoba et al.
Nov 01, 2011 read hypoglycemic activity of buchholzia coriacea capparaceae seeds in streptozotocininduced diabetic rats and mice, experimental and toxicologic pathology on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Effects of methanol extract of buchholzia coriacea fruit. The hypoglycemic and antioxidant effects of the methanolic extract of buchholzia coriacea fruits in streptozotocininduced diabetic rats were investigated. Between 2000 and 2002, he was the subdean of the faculty of science of the university of lagos. See status, confidence level, source for definitions. Buchholzia coriacea bc, commonly known as wonderful kola, is a perennial plant which grows as a tree.
In gabon the plant buchholzia coriacea is sometimes cultivated as. Thirty male wistar rats, weighing between 100 120 g were used and randomly assigned into three groups of 5 rats each per experiment. Swaps collected from banana, guava, tomato and spinach were cultured using nutrient agar, microorganisms characterized culturally and morphologicallyand subjected to biochemical tests to identify principal microorganisms. Antibacterial activity of the biosynthesized agnps was evaluated against some selected pathogenic microorganisms. Thirty male wistar rats, weighing between 100 120 g were used and randomly assigned into three groups of 5 rats each per.
Hypercholesterolemia is a condition characterized with high level of cholesterol in the blood of animals. Buchholzia coriacea, glibenclamide, insulin resistance. The results of the present study showed that buchholzia coriacea seed methanol extract pos. Us8603545b2 cosmetic and pharmaceutical uses of an. The antitrypanosomal activity of the methanol extract of buchholzia coriacea seed against a field strain of trypanosoma congolense was investigated using experimentally infected mice of both sexes. It was tolerated up to dose of 2000 mg kg1 orally in rats. Chemoprotective effects of butanol fraction of buchholzia coriacea.
It is caused by a variety of factors which can either be environmental or genetic. Seeds were obtained from ogbete main market, enugu state,identified,dried and grounded using a miller machine. It is a shrub, evergreen, with a dense crown, large glossy, and leathery leaves mbata et al. At doses of 10 mgkg, 25 mgkg and 50 mgkg, the extracts were tested against eudrilus eugeniae earthworm and bunostomum phlebotomum. It covers as far as possible the prescribed syllabuses of several indian universities and will meet the needs of degree students not only in india but abroad as well. Investigations aimed at identifying and isolating the. Buchholz who collected plants in cameroon in the late 19th century 18. Intestinal handling of glucose in buccholzia coriacea treated. Journal of pharmacy and nutrition sciences, 000000 1 effects. Neurotoxicity occurs as a result of exposure to neurotoxins in the environment, of which nan3 is a potent neurotoxin.
Some people call this plant buchholzia coriacea when using the scientific language. Development of extraction protocol for phenolic compounds in. Buchholzia species buchholzia coriacea name synonyms buchholzia engleri gilg buchholzia macrophylla pax homonyms buchholzia coriacea engl. The effect of buccholzia coriacea on renal function indices. However, people from the yoruba and igbo ethnical groups call it differently. Evidences abound for its diverse medicinal potentials. A cosmetic or dermopharmaceutical composition including an extract of a plant belonging to the genus buchholzia and at least one auxiliary andor additive is provided. He was appointed the head of the department of chemistry between 2002 and 2005. Antimicrobial, antiinflammatory, and chemical evaluation. Buchholzia coriacea is a forest tree with large glossy leathery leaves and conspicuous cream white flowers at the end of its branches.
They refer to this plant as to the okpokolo, uwuro, or aponmu. Determination of chemical composition, nutritional quality. Immunomodulatory activity of buchholzia coriacea seed methanol. The fresh leaves of buchholzia coriacea was obtained from ganboro reserve at lanke camp about 4km from idanre,ondo state, nigeria and was identified by a. The amelioration of carbon tetracholride induced toxicities. Neuroprotective effects of buchholzia coriacea seed extract.
Please note that this is a trial program and may end. Buchholzia coriacea bc seed was washed, sliced, dried, pulverized and mixed with standard ration at 2. Buchholzia coriacea is a tropical plant used in traditional medicine ejikeugwu et al, 2015. The ethanolic extract of buchholzia coriacea seed caused larval deaths of the infective stage larvae of haemonchus contortus and heligmosomoides polygrus at various concentrations in vitro nweze and asuzu, 2006.
The seeds gave the plant its common name because of its popular usage in traditional medicine keay, 1989 such as in the cure for diabetes. Pdf buchholzia coriacea wonderful cola, belonging to the family of. The present study evaluates the possible hypoglycemic activity and ameliorative effects of oral administration of ethanol extracts eebc and butanol fraction bfbc of buchholzia coriacea seeds, a plant in use traditionally for treating diabetes, hypertension, rheumatism, cold, cough and catarrh, in streptozotocin stzinduced diabetic mice and rats. Diet containing seeds of buchholzia coriacea accelerates. Treatment with 150, 300 and 600 mg kg1 of the extract induced significant p free access to water, and standard diet was given ad libitum. Phytochemical and nutritive qualities of dried seeds of. Safe african medicinal plants for clinical studies. However, study to demonstrate its involvement in t2d experimental. The biosynthesised agnps were characterised using uvvisible, fourier transmission infrared spectroscope ftir, energy dispersive xray. Intestinal handling of glucose in buccholzia coriacea. The seeds of buchholzia coriacea engler capparaceae are used in eastern. The anthelmintic potentials of the chloroform and methanol extracts of buchholzia coriacea engler seed were investigated. Buchholzia coriacea seeds at 50mgkg, 100mgkg and 200mgkg respectively.
Analgesic activity of the methanolic seed extract of buchholzia coriacea article pdf available in research journal of pharmaceutical, biological and chemical sciences 21. Determination of the potentials of aqueous and ethanolic. Phytochemical and nutritive qualities of dried seeds of buchholzia coriacea. Request pdf on jan 1, 2018, sylvester chibueze izah and others published medicinal potentials of buchholzia coriacea wonderful kola find, read and cite all the research you need on researchgate. Its role in intestinal glucose uptake was investigated. To investigate the anticolitic effects of diet containing seeds of buchholzia coriacea b. The leaves and seeds are known scientifically to possess antihelmintic, antibacterial and. Comparative evaluation of phytoconstituents, antibacterial. The seeds gave the plant its common name because of its popular usage in traditional medicine. A method for the cosmetic treatment of the skin or scalp and a method for the treatment of skin inflammation includes administering to a patient in need thereof a composition including an effective amount of a plant extract from.
This study was designed to evaluate the therapeutic potentials and neuroprotective effects of methanol extract of buchholzia coriacea bc seeds on sodium azide nan3 induced neurotoxicity of the prefrontal cortex in male wistar rats. Effect of buchholzia coriacea wonderful kola on microflora. Oluwole babafemi familoni is a professor of chemistry at the university of lagos and member of the governing council of the institute of chartered chemists of nigeria. The seeds of the plant are edible, taste peppery and are known to have great medicinal value which gave the plant its common name wonderful kola 19. Anthelmintic activities of chloroform and methanol extracts. Antidiabetic property and phytochemical composition of. Buchholzia coriacea belongs to the family, capparaceae and is widely distributed in several tropical countries. It belongs to the family capparaceae and genus buchholzia quattrocchi, 1999. The information presented is presently mostly based on herbarium sheet labels and annotations and not checked for correctness. The proximate nutrient composition of the standard and prepared rations was determined.
This study examined the nephrotic effect of buchholzia coriacea formulated diet in sucrosefed pregnant rats and their offspring. Preliminary study on the effects of buchholzia coriacea seed extract. At the sixth week, colitis was induced by intrarectal administration of 1 ml200. Biochemistry project topics and materials projectng. It has a dense crown, large glossy leathery leaves arranged spirally and clustered at the ends of the branches, and conspicuous creamwhite flowers in racemes at the end of the branches 10. The seeds were washed, chopped into pieces and air dried. The seeds of buchholzia coriacea engler capparaceae are used in eastern nigeria to treat feverish conditions, and to treat malaria. Male wistar rats 70100 g were fed with standard diets control group or with same diet containing b. Antibacterial activity of crude seed extracts of buchholzia. Buchholzia coriacea, commonly known as wonderful kola is a perennial plant which grows as a tree. Phytochemical and nutritive quality of dried seeds of. Engler in carbon tetrachloride induced toxicity or damage in male albino rats.
The sixth edition of botany for degree students presents a thorough revision of the whole text, including the rewriting of many sections and the addition of several new topics on the basis of recent research. Hypoglycemic activity of buchholzia coriacea capparaceae. Its use in folklore medicine is popular for diabetes. The crude extract exhibited potent hypoglycemic activities at the test doses 150, 300 and 600 mg kg 1 within the duration of study. The buchholzia coriacea wonderful kola was washed, extracted using water and ethanol and screened for phytochemical compounds. Antihypercholesterolemic activity of ethanolic extract of. Results and discussion results of preliminary phytochemical screening of the seed extracts of b.
The effects of methanol extract of buchholzia coriacea seed was studied on male reproductive system of albino rats. The least concentration, at which no visible growth was observed, was noted as the mbc. This study was designed to evaluate the therapeutic potentials and neuroprotective effects of methanol extract of buchholzia coriacea bc seeds on sodium azide nan 3 induced neurotoxicity of the prefrontal cortex in male wistar rats. The effect of buccholzia coriacea on renal function. The antimicrobial activity of the nhexane, methanol and aqueous extracts of b.
Feb 23, 2011 the anthelmintic potentials of the chloroform and methanol extracts of buchholzia coriacea engler seed were investigated. Buchholzia coriacea methanol fruit extract was safe up to a dose of 2000 mg kg1 and did not cause mortality in rats. Journal of pharmacy and nutrition sciences, 000000 1. Buchholzia coriacea figure 1 the pictures of buchholzia coriacea tree, leaves and seeds. Medicinal potentials of buchholzia coriacea wonderful kola. Capparidaceae is a forest tree with large, glossy, leathery leaves and conspicuous cream white flowers in racemes at the end of the bran ches. Investigation of the antitrypanosomal activity of buchholzia.
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